BCMB 4020 (4 hr) Biochemistry and Molecular Biology II is the second half of a
two-semester sequence (BCMB 4010 - BCMB 4020) intended for biochemistry majors,
preprofessional students, and others interested in an intensive introduction to
biochemistry and molecular biology.  This is a primarily lecture-based course
designed to provide students with a coherent, integrated introduction to the
principles, methods, and results of current biochemical and molecular biology research.  
The student will be expected to acquire a basic understanding of the following
subject areas:  1) primary pathways and enzymes of carbohydrate metabolism, 2)
primary pathways and enzymes of lipid metabolism, 3) primary pathways and enzymes of
nitrogen metabolism, 4) DNA replication and RNA synthesis, 5) the genetic code and
protein synthesis, and 6) respiration and photosynthesis. BCMB 4010 (or BCMB 3100) is
a prerequisite for BCMB 4020.  Students who successfully complete the two-semester
sequence should be able to comprehend primary literature in biochemistry and
molecular biology and should also be equipped to take more advanced courses in or
requiring these disciplines.  
	
Student performance will be assessed by written examinations.  There will be three
examinations during the course of the semester plus a cumulative final.  The
examinations will be in-class, closed-book exams and will include a variety of
question formats (multiple choice, problems, short essay, etc.). 

Student evaluations will be obtained at the end of the semester in accordance with
university and department policy.

Topics will include the primary metabolic pathways, bioenergetics, photosynthesis,
respiration, replication, transcription, and translation.  An outline of the syllabus
is as follows. The numbers in parentheses refer to the relevant chapter (and number
of pages) in the recommended textbook for the course, Biochemistry by Garrett &
Grisham (Saunders College Publishing).

Metabolism:  An Overview (#18 - 42p)
Glycolysis (#19 - 29 p)
Tricarboxylic Acid Cycle (#20 - 33 p)
Oxidative Phosphorylation (#21 - 33p)
Photosynthesis (#22 - 31p)
Gluconeogenesis (#23 - 30p)
Fatty Acid Catabolism (#24 - 25p) 
Lipid Biosynthesis (#25 - 48p) 
Amino Acid Metabolism (#26 - 45p)
Nucleotides (#27 - 26 p)
Metabolic Integration (#28 - 19p)
DNA: Genetic Information (#29 - 32p) 
DNA Replication/Repair (#30 - 28 p) 
Transcription (#31 - 52p) 
The Genetic Code (#32 - 18p)
Protein Synthesis (#33 - 36p)