| Course ID: | PBGG(CRSS)(HORT) 8874. 1 hour. |
| Course Title: | Genomic Selection |
Course
Description: | Concepts, implementation, and application of predicting organism
phenotypes from genome-wide marker sets. This course covers
genomic selection (GS), an application of genome-wide
prediction in order to accelerate breeding and reduce
phenotyping costs. Course also covers both theory and practice,
and requires a good understanding of mixed linear models and
genome-wide marker sets. |
| Oasis Title: | Genomic Selection |
| Prerequisite: | PBGG(CRSS)(HORT)(PBIO) 8871 or PBGG(CRSS)(HORT)(PBIO) 8872 or permission of department |
| Pre or Corequisite: | PBGG(CRSS)(HORT)(PBIO) 8871 or PBGG(CRSS)(HORT)(PBIO) 8872 or permission of department |
Semester Course
Offered: | Offered spring semester every odd-numbered year. |
| Grading System: | A-F (Traditional) |
|
| Course Objectives: | The objective will be for students to learn concepts,
implementation, and application of predicting organism
phenotypes from genome-wide marker sets.
Learning objectives:
1.Understand the theoretical background of genomic selection.
2.Know what parameters make genomic selection likely to succeed
(and what can make it fail).
3.Be able to use several basic genomic selection algorithms and
verify that the results are trustworthy. |
| Topical Outline: | Background and purposes of genomic selection (GS)
Considerations when designing/performing a GS experiment
Relatedness among samples
Frequency of model retraining
Cross-validation accuracy
Gains versus phenotypic selection
Types of GS models
Ridge Regression
gBLUP
Bayesian methods
Software for performing GS |