**Course** Description: | Further study of statistical concepts for bioinformatics.
Statistical topics include estimation and hypothesis testing,
maximum likelihood, Bayesian analysis, multiple testing, Markov
chains, MCMC methods, and random walks. These are applied in
BLAST, statistical modeling of DNA sequence, multiple sequence
alignment, models for sequence evolution, phylogenetic analysis
and other topics. |

**Topical Outline:** | Estimation and hypothesis testing, maximum likelihood, Bayesian
analysis, multiple testing, Markov chains, MCMC methods, and
random walks, BLAST, statistical modeling of DNA sequence,
multiple sequence alignment, models for sequence evolution,
phylogenetic analysis, and other topics. |