Course ID: | ECOL(BIOL) 4150/6150-4150L/6150L. 4 hours. 3 hours lecture and 2 hours lab per week. |
Course Title: | Population Biology of Infectious Diseases |
Course Description: | Ecology and evolution of infectious diseases that affect
free-living animals, plants and human populations. Topics
include pathogen life history and transmission modes,
epidemiology and impacts on hosts, evolution of resistance and
virulence, emerging infectious diseases, and the role of
parasites in wildlife conservation. |
Oasis Title: | POP BIOL INFECT DIS |
Prerequisite: | (BIOL 1104 or BIOL 1108-1108L or PBIO 1220) and (STAT 2000 or MATH 2200 or MATH 2250) |
Semester Course Offered: | Offered spring semester every year. |
Grading System: | A-F (Traditional) |
|
Course Objectives: | 1. Provide an understanding of the biology of parasites and
infectious diseases, integrating basic concepts with real-world
examples
2. Increase familiarity with quantitative approaches for
studying
infectious disease dynamics at the population level
3. Review historical development and current research in the
field of disease ecology
4. Enhance appreciation for the taxonomic and biological
diversity of parasitic organisms and host responses to infection
5. Enhance appreciation for the importance of parasites in
wildlife conservation and management
6. Consider the role of ecology and evolution in predicting
disease emergence and responding to epidemics |
Topical Outline: | PART 1. THE BASICS: EPIDEMIOLOGY AND PARASITE BIOLOGY
Introduction: Basic terminology and diversity of parasites
Population growth, population regulation and statistical
epidemiology
Population biology of microparasites
Rinderpest in the Serengeti, dead seals in the North Sea
Measles and childhood diseases: herd immunity and vaccination
Parasitic helminths: T.tenuis and red grouse
Helminths of humans: Ascaris, filariasis and hookworm
Rots, scabs, smut and blight: the biology of plant pathogens
Invertebrate pathology: forest pest cycles and insect mushrooms
PART 2. ECOLOGICAL HETEROGENEITY
Parasites and host behavior
It bit me: vector-borne pathogens, ticks and mosquitoes
Birds, bees and STDs
Complex dynamics and social mixing
Key hosts and superspreaders
Patterns of spatial spread
Metapopulation biology of disease
Community effects and multi-host pathogens
Keeping the herds healthy: predators and infectious disease
PART 3. HOST IMMUNITY AND PATHOGEN EVOLUTION
Vertebrate immunity: innate and adaptive
Population dynamics of the immune response
Immunity and resistance in plants and invertebrates
Evolution of host resistance: tradeoffs and constraints
Parasites and sexual selection
Evolution of pathogen virulence
Molecular phylogeny of pathogens
Host-parasite coevolution and cospeciation
PART 4. CONSERVATION, CONTROL, AND EMERGING INFECTIOUS DISEASES
Influenza, Ebola, BSE; emergent pathogens and disappearing cures
Worms in a warmer world; parasites and global change
Evaluating disease risks to threatened wildlife
Drug treatment and drug resistance
Role of host-pathogen evolution in disease emergence
Darwinian medicine |
Honor Code Reference: | All academic work must meet the standards contained in "A
culture of honesty." Students are responsible for informing
themselves about those standards before performing academic
work.
The link to more detailed information about academic honesty can
be found at: http://www.uga.edu/ovpi/honesty/acadhon.htm |