Course ID: | EHSC 4490. 3 hours. |
Course Title: | Environmental Toxicology |
Course Description: | Extent and significance of toxic agents in the environment, and the physical, chemical, and biological processes which determine their behavior, fate, and ultimate effect on human health. |
Oasis Title: | Environmental Toxicology |
Prerequisite: | CHEM 2211 and CHEM 2211L and (BIOL 1104 or BIOL 1108-1108L) |
Semester Course Offered: | Offered fall semester every year. |
Grading System: | A-F (Traditional) |
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Course Objectives: | 1. Summarize the nature of toxicants.
2. Explain the effects of environmental toxicants on human
health.
3. Compare methods of environmental toxicants and detection of
poisons.
4. Analyze treatment methods to ameliorate environmental
toxicant exposure.
5. Synthesize basic science concepts from anatomy, physiology,
and biochemistry to facilitate the discussion of the principles
and mechanisms of toxicant action on specific organs and systems.
6. Describe the principles of the dose response curve from data
sets.
7. Critique chemical and microbial risk assessments
(significance, reliability, and interpretation).
8. Interpret information from the four basic elements of risk
assessment (hazard identification, exposure assessment, hazard
characteristics, and risk characterization).
9. Model the three main steps of carcinogenesis. |
Topical Outline: | In addition to the topics listed below, the course may include
guest lectures from scientists and toxicologists who are
experts in their respective fields.
• The theme of environmental changes and environmental health,
natural occurrence and categories of environmental toxicants,
fate and transport of toxicants in environment, and
bioaccumulation of persistent environmental toxicants, as well
as regulations and policies in controlling their environmental
pollution or contamination.
• General Principles of Toxicology (absorption of toxicants;
distribution and storage of toxicants; biotransformation of
chemicals; excretion of toxic chemicals; factors modifying
metabolism; mechanisms of toxic effects and conventional
toxicity tests).
• Organ-Specific Toxicology (mutagenesis and carcinogenesis;
liver toxicology and immunotoxicology; renal toxicology;
neurotoxicology; dermatoxicology and toxicology of eye;
inhalation toxicology; cardiovascular toxicology; reproductive
toxicology; developmental toxicology).
• Assessment of Toxicity (overview of risk assessment and
assignment of risk assessment projects; risk assessment-hazard
evaluation, exposure assessment, risk assessment-toxicity
assessment, risk characterization, environmental justice).
• Classes of Toxic Chemicals (dietary toxins and food additives
and therapeutic drugs and drugs of abuse; volatile organic
compounds and solvents; industrial toxicants; metals and
radionucleotides; pesticides; toxicity of chemicals in water,
air, and soil; ecotoxicology). |
Honor Code Reference: | All academic work must meet the standards contained in "A Culture of Honesty."
Each student is responsible to inform themselves about those standards before
performing any academic work. Each student is expected to closely adhere to
the University of Georgia honor code. |