Course Listing For BCMB

BCMB(BIOL)(CHEM) 3100. Introductory Biochemistry and Molecular Biology. 3 hours.
Oasis Title: INTRODUCT BIOCHEM.
Prerequisite: CHEM 2211 and CHEM 2211L.
The structure and function of biological molecules, enzymology, metabolism and bioenergetics, and recombinant DNA technology.
Offered fall, spring, and summer semesters every year.

BCMB 4010/6010. Biochemistry and Molecular Biology I. 3 hours.
Oasis Title: BIOC & MOL BIOL I.
Undergraduate prerequisite: CHEM 2211 and CHEM 2211L.
A comprehensive treatment of biochemistry and molecular biology stressing structures of biological molecules, including proteins, nucleic acids, carbohydrates, and lipids, enzymology and selected aspects of metabolism and bioenergetics.
Offered fall semester every year.

BCMB 4020/6020. Biochemistry and Molecular Biology II. 3 hours.
Oasis Title: BIOC & MOL BIOL II.
Undergraduate prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
A comprehensive treatment of biochemistry and molecular biology stressing aspects of metabolism, metabolic regulation, bioenergetics, and recombinant DNA methodologies.
Offered spring semester every year.

BCMB 4030L/6030L. Laboratory Techniques in Biochemistry and Molecular Biology. 3 hours. 1 hour lecture and 6 hours lab per week.
Oasis Title: BIOC & MOL BIOL LAB.
Undergraduate prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Basic techniques in biochemistry and molecular biology, including enzyme assays and purification, nucleic acid purification and characterization, chromatography, spectroscopy, and other modern methods.
Offered fall semester every year.

BCMB(CHEM) 4110/6110. Physical Biochemistry. 3 hours.
Oasis Title: PHYS BIOCHEM.
Undergraduate prerequisite: MATH 2210.
Undergraduate prerequisite or corequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010 or PHYS 1112-1112L or PHYS 1212-1212L.
The principles of physical chemistry applied to biological molecules and systems, including current approaches in structural biology.
Offered fall semester every year.

BCMB 4120/6120. Human Biochemistry and Disease. 3 hours.
Oasis Title: HUMAN BIOCHEMISTRY.
Undergraduate prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Integrated treatment of human biochemistry and selected topics on the biochemical basis of human disease. Examples will be given of inheritable and acquired disorders.
Offered fall semester every year.

BCMB 4130/6130. Biotechnology. 3 hours.
Oasis Title: BIOTECHNOLOGY.
Undergraduate prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Applied aspects of biochemistry and molecular biology in various fields, with emphasis on the use of recombinant DNA methods and protein engineering.
Offered spring semester every year.

BCMB 4960L. Laboratory Research in Biochemistry and Molecular Biology I. 3-5 hours. 9-15 hours lab per week.
Oasis Title: BIOC&MOL BIO RES I.
Prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Basic techniques in biochemistry and molecular biology, application of the scientific method, and preparation of a written scientific report. For students with little or no laboratory experience.
Offered fall, spring, and summer semesters every year.

BCMB 4960H. Laboratory Research in Biochemistry and Molecular Biology I (Honors). 3-5 hours. 9-15 hours lab per week.
Oasis Title: BIOC MOL BIO I.
Prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010 or permission of Honors.
Basic techniques in biochemistry and molecular biology, application of the scientific method, and preparation of a written scientific report. For Honors students with little or no laboratory experience.
Offered fall, spring, and summer semesters every year.

BCMB 4970H. Laboratory Research in Biochemistry and Molecular Biology II (Honors). 3-5 hours. Repeatable for maximum 10 hours credit. 9-15 hours lab per week.
Oasis Title: BIOC&MOL BIO RES II.
Prerequisite: BCMB 4030L/6030L or BCMB 4960H or permission of Honors.
Advanced techniques in biochemistry and molecular biology, application of the scientific method, and preparation of a written scientific report. For Honors students with some laboratory experience.
Offered fall, spring, and summer semesters every year.

BCMB 4970L. Laboratory Research in Biochemistry and Molecular Biology II. 3-5 hours. Repeatable for maximum 10 hours credit. 9-15 hours lab per week.
Oasis Title: BIOC&MOL BIO RES II.
Prerequisite: BCMB 4030L/6030L or BCMB 4960H.
Advanced techniques in biochemistry and molecular biology, application of the scientific method, and preparation of a written scientific report. For students with some laboratory experience.
Offered fall, spring, and summer semesters every year.

BCMB 4990H. Honors Thesis in Biochemistry and Molecular Biology. 3-5 hours. 9-15 hours lab per week.
Oasis Title: BMB HONORS THESIS.
Prerequisite: (BCMB 4010/6010 and BCMB 4030L/6030L) or BCMB 4960H or permission of Honors.
Prerequisite or corequisite: BCMB 4020/6020.
Laboratory research in biochemistry and molecular biology under the supervision of a faculty member. A thesis summarizing the literature in the field and the student's research findings is required.
Offered fall, spring, and summer semesters every year.

BCMB 6000. General Biochemistry and Molecular Biology. 3 hours.
Oasis Title: BIOCHEM & MOL BIOL.
Not open to students with credit in BCMB 4010/6010 or BCMB 4020/6020 or BCMB 8010 or BCMB 8020.
Prerequisite: CHEM 2212 and CHEM 2212L.
Beginning intensive one-semester graduate-level course in biochemistry and molecular biology covering the structure and function of biological molecules, enzymology, metabolism, bioenergetics, and recombinant DNA technology.
Offered fall semester every year.

BCMB 7000. Master's Research. 1-10 hours. Repeatable for maximum 20 hours credit.
Oasis Title: MASTER'S RESEARCH.
Prerequisite: Permission of department.
Research while enrolled for a master's degree under the direction of faculty members.
Non-traditional format: Independent research under the direction of a faculty member.
Offered fall, spring, and summer semesters every year.

BCMB 7300. Master's Thesis. 1-10 hours. Repeatable for maximum 20 hours credit.
Oasis Title: MASTER'S THESIS.
Prerequisite: Permission of department.
Thesis writing under the direction of the major professor.
Non-traditional format: Independent research and thesis preparation.
Offered fall, spring, and summer semesters every year.

BCMB 8010. Advanced Biochemistry and Molecular Biology I. 4 hours.
Oasis Title: ADV BIOC/MOL BIOL I.
Prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Advanced biochemistry and molecular biology stressing thermodynamic principles in biochemistry, structural biology, enzymology, and aspects of metabolism and bioenergetics.
Offered fall semester every year.

BCMB 8020. Advanced Biochemistry and Molecular Biology II. 4 hours.
Oasis Title: ADV BIOCHEM II.
Prerequisite: BCMB 8010.
Advanced biochemistry and molecular biology stressing metabolism and bioenergetics, replication, transcription, RNA processing, genetic codes, translation, membrane transport, and signal transduction.
Offered spring semester every year.

BCMB 8030. Introduction to Research in Biochemistry and Molecular Biology. 3 hours.
Oasis Title: INTRO RES BMB.
Prerequisite: Permission of department.
Overview of current departmental research and introduction to research facilities. Training and practical experience in oral presentation, scientific writing, and grant preparation.
Offered fall semester every year.

BCMB(CHEM) 8040. Advanced Physical Biochemistry. 3 hours.
Oasis Title: ADV PHYS BIOC.
Prerequisite: Permission of department.
Principles in physical chemistry and biophysics to biological macromolecules, including structural biology, hydrodynamics, electronic and magnetic resonance spectroscopy, and crystallography.
Offered spring semester every year.

BCMB 8050. Cellular and Molecular Biochemistry. 1 hour. Repeatable for maximum 5 hours credit.
Oasis Title: CELL & MOL BIOC.
Prerequisite: BCMB 8020 or permission of department.
Advanced molecular and cellular biochemistry, including structure, biosynthesis, and assembly of cell proteins and nucleic acids.
Non-traditional format: Selected readings and meetings with speakers in the annual BMB Symposium.
Offered spring semester every year.

BCMB 8060. Biochemistry and Molecular Biology Seminar. 2 hours. Repeatable for maximum 20 hours credit.
Oasis Title: BIOC & MOL BIOL SEM.
Prerequisite: BCMB 8020.
Seminar dealing with various topics in current biochemistry and molecular biology.
Non-traditional format: Grading of A-F will be used when the student presents a seminar; grading of S/U will be used when attendance is required but a seminar is not given.
Offered fall and spring semesters every year.

BCMB 8070. Research Discussion. 1 hour. Repeatable for maximum 10 hours credit.
Oasis Title: RESEARCH DISCUSSION.
Prerequisite: BCMB 8010 or permission of department.
Seminar focused on current research in biochemistry and molecular biology.
Offered fall, spring, and summer semesters every year.

BCMB 8080. Current Literature in Biochemistry and Molecular Biology. 1 hour. Repeatable for maximum 6 hours credit.
Oasis Title: BIOC & MOL BIOL LIT.
Prerequisite: BCMB 8020.
Journal club in selected topics in cell and molecular biochemistry.
Not offered on a regular basis.

BCMB 8100. Advanced Topics in Biochemistry and Molecular Biology. 1 hour. Repeatable for maximum 10 hours credit.
Oasis Title: ADVANCED TOPICS.
Prerequisite: BCMB 8020.
Selected areas in current molecular and cell biochemistry. Topics will change on a regular basis.
Not offered on a regular basis.

BCMB(CHEM) 8110. Advanced Topics in Protein Structure-Function Relationships. 3 hours.
Oasis Title: PROTEIN STR/FUNC.
Prerequisite: BCMB 8010.
The relationship of protein structure to biological function, including protein folding, conformation, stability, and enzyme mechanisms.
Offered fall semester every even-numbered year.

BCMB 8120. Advanced Topics in Gene Expression. 2 hours.
Oasis Title: NUCLEIC ACIDS.
Prerequisite: BCMB 8010.
Biochemistry and molecular biology of nucleic acids, with emphasis on biosynthesis, structure, and function.
Offered spring semester every even-numbered year.

BCMB 8130. Advanced Topics in Glycobiology. 2 hours.
Oasis Title: GLYCOBIOLOGY.
Prerequisite: BCMB 8010.
Complex carbohydrates and glycoconjugates, including biosynthesis, structure, and biological function.
Offered fall semester every odd-numbered year.

BCMB 8140. Advanced Topics in Genomics and Bioinformatics. 2 hours.
Oasis Title: GENOMICS&BIOINFORMA.
Prerequisite: BCMB 8010.
Contemporary approaches in the genomics of bacteria, archaea and eucarya, including computer applications on the use of various data bases.
Offered fall semester every odd-numbered year.

BCMB 8150. Advanced Topics in Cellular Communication and Regulation. 2 hours.
Oasis Title: CELL COMM & REG.
Prerequisite: BCMB 8010.
Molecular mechanisms of intra- and inter-cellular communication, including the role of hormones, cytokines, neurotransmitters and receptors.
Offered spring semester every even-numbered year.

BCMB 8160. Advanced Topics in the Biochemical Basis of Human Disease. 2 hours.
Oasis Title: BIOC HUMAN DIS.
Prerequisite: BCMB 8010.
The molecular and cellular basis of human disease with emphasis on genetic and acquired disorders.
Offered spring semester every odd-numbered year.

BCMB 8170. Advanced Topics in Plant Biochemistry and Molecular Biology. 2 hours.
Oasis Title: PLANT BIOCHEMISTRY.
Prerequisite: BCMB 8010.
Advanced treatment of plant biochemistry and molecular biology, including photosynthesis and nitrogen fixation.
Offered spring semester every odd-numbered year.

BCMB(CHEM) 8180. X-Ray Crystallography. 3 hours. 2 hours lecture and 2 hours lab per week.
Oasis Title: CRYSTALLOGRAPHY.
Prerequisite: BCMB 8010 and BCMB 8040.
The basic principles of x-ray crystallography with major application to protein structure determination, including laboratories on crystallization techniques and data collection.
Offered spring semester every year.

BCMB(CHEM) 8190. NMR Spectroscopy of Biomolecules. 3 hours.
Oasis Title: BIOL NMR SPEC.
Prerequisite: BCMB 8010 and BCMB 8040.
NMR spectroscopy with applications to proteins and other biopolymers. Special attention will be given to methods of structure determination.
Offered fall semester every odd-numbered year.

BCMB(CHEM) 8200. Molecular Modeling and Structure Computations. 3 hours. 1 hour lecture and 4 hours lab per week.
Oasis Title: MOL MOD & STRUC COM.
Prerequisite: BCMB 8010 or permission of department.
Modern biomolecular modeling and structure computations with emphasis on the application of molecular dynamics simulations to proteins, carbohydrates, and protein-ligand complexes. Lectures will be complemented with laboratory sections on the use of modeling software and computer hardware.
Offered fall semester every even-numbered year.

(BCMB)CHEM 8220. Physical Methods in Inorganic and Bioinorganic Chemistry. 4 hours. 3 hours lecture and 3 hours lab per week.
Oasis Title: PHYS METH INORG CHM.
Prerequisite: CHEM 8210.
Physical methods used in inorganic and bioinorganic chemical research including UV/visible/near IR absorption spectroscopy, (magnetic) circular dichroism, electron paramagnetic resonance, nuclear magnetic resonance, Mossbauer and X-ray absorption spectroscopies, single crystal x-ray diffraction, and magnetochemistry.
Offered spring semester every year.

(BCMB)CHEM 8250. Bioinorganic Chemistry. 3 hours.
Oasis Title: BIOINORG CHEM.
Prerequisite or corequisite: BCMB 6000 or BCMB 8010 or CHEM 6400 or permission of department.
Biological processes and molecules, mainly proteins and nucleic acids, which incorporate metal ions. Topics include metal binding to biopolymers, the roles of metal ions in biological processes such as electron transfer, atom or group transfer, and the use of metal complexes as therapeutic agents.
Offered fall semester every odd-numbered year.

(BCMB)CHEM 8330. Molecular Modeling. 3 hours.
Oasis Title: MOLECULAR MODELING.
Computational studies to calculate the structures of organic molecules. Specific training is given in the application of the molecular mechanics method and the MM-3 software package, ab initio calculations using the Gaussian software package, and other computational schemes. Evaluation of computational results.
Not offered on a regular basis.

(BCMB)CBIO(MIBO) 8520. Topics in Biochemistry and Molecular Genetics of Parasites. 3 hours. Repeatable for maximum 6 hours credit. 1 hour lecture and 2 hours lab per week.
Oasis Title: MOLEC PARASITOL.
Prerequisite: BCMB 8020 and GENE 8930.
Parasite cellular biochemistry and molecular genetics with potential for rational drug design. Topics include DNA replication, RNA editing, nucleic acid salvage pathways, polyamine metabolism, and glycosylphosphatidylinositol (GPI) anchors.
Offered spring semester every odd-numbered year.

(BCMB)CHEM 8810. Mass Spectrometry. 3 hours.
Oasis Title: MASS SPECTROMETRY.
Modern methods of mass spectrometry covering fundamental principles, instrumentation, and data interpretation. New techniques for the structural analysis of biomolecules.
Offered fall semester every year.

(BCMB)GENE 8910. DNA Modeling. 2 hours. 1 hour lecture and 3 hours lab per week.
Oasis Title: DNA MODELING.
The building of space filling models to help students understand the structure/function relationships of RNA and DNA. Computer modeling approaches will also be taught.
Offered fall semester every year.

(BCMB)BTNY(GENE)(PATH) 8960. Fungal Genetics. 3 hours.
Oasis Title: FUNGAL GENETICS.
Prerequisite: Permission of department.
The genetics of the fungi emphasizing classical and modern molecular approaches.
Offered spring semester every even-numbered year.

BCMB 8990. Problems in Biochemistry and Molecular Biology. 1-10 hours. Repeatable for maximum 20 hours credit.
Oasis Title: PROB BIOC&MOL BIOL.
Prerequisite: Permission of department.
Focused research, advanced readings, and tutorials with faculty members.
Non-traditional format: Students will meet with faculty members on a regular basis.
Offered fall, spring, and summer semesters every year.

BCMB 9000. Doctoral Research. 1-15 hours. Repeatable for maximum 45 hours credit.
Oasis Title: DOCTORAL RESEARCH.
Prerequisite: Permission of department.
Research while enrolled for a doctoral degree under the direction of faculty members.
Non-traditional format: Independent research under the direction of a faculty member.
Offered fall, spring, and summer semesters every year.

BCMB 9300. Doctoral Dissertation. 1-15 hours. Repeatable for maximum 30 hours credit.
Oasis Title: DOCT DISSERTATION.
Prerequisite: Permission of department.
Dissertation writing under the direction of the major professor.
Non-traditional format: Independent research and preparation of the doctoral dissertation.
Offered fall, spring, and summer semesters every year.