By the end of the course, the students should be able to:
- Describe the organ systems most often affected by toxic 
agents
- Describe the basic principles required for an agent to exert 
a toxic effect (absorption, distribution, biotransformation, 
excretion)
- Compare/contrast mechanisms of toxicity from different 
classes of toxic chemicals
- Design an environmental risk assessment to evaluate risk from 
exposure to a toxic agent
- Interpret data from toxicity studies described in the 
literature
- Critique contemporary journal articles describing toxicity 
tests of environmental agents

The course syllabus is a general plan for the course; 
deviations announced to the class by the instructor may be 
necessary.

In addition to the topics listed below, the course may include 
guest lectures from scientists and toxicologists who are 
experts in their respective fields.

• General Principles of Toxicology (absorption of toxicants; 
distribution and storage of toxicants; biotransformation of 
chemicals; excretion of toxic chemicals; factors modifying 
metabolism; mechanisms of toxic effects and conventional 
toxicity tests)

• Organ-Specific Toxicology (mutagenesis and carcinogenesis; 
liver toxicology and immunotoxicology; renal toxicology; 
neurotoxicology; dermatoxicology and toxicology of eye; 
inhalation toxicology; cardiovascular toxicology; reproductive 
toxicology; developmental toxicology)

• Assessment of Toxicity (dose response relationship, overview 
of risk assessment; risk assessment hazard evaluation, exposure 
assessment, risk assessment-toxicity assessment, risk 
characterization, environmental justice, analysis and 
interpretation of experimental data, design of experiments for 
carcinogens and non-carcinogens

• Classes of Toxic Chemicals (dietary toxins and food additives 
and therapeutic drugs and drugs of abuse; volatile organic 
compounds and solvents; industrial toxicants; metals and 
radionucleotides; pesticides; toxicity of chemicals in water, 
air and soil; ecotoxicology)

All academic work must meet the standards contained in "A 
Culture of Honesty." Each student is responsible to inform 
themselves about those standards before performing any academic 
work. Each student is expected to closely adhere to the 
University of Georgia Honor Code.