Course Description
An introduction to evolutionary genetics combining both mathematical theory and experimental and field research and covering the basics of population genetics, evolutionary ecology, quantitative genetics, and molecular evolution.
Athena Title
Fundamentals Evolutionary Gene
Prerequisite
GENE 3000-3000D or GENE 3000H
Corequisite
GENE 8150L
Semester Course Offered
Offered fall
Grading System
A - F (Traditional)
Course Objectives
The successful student will know how to: 1. analyze basic concepts in evolutionary genetics in terms of mathematical models. 2. pose and test hypotheses drawn from concepts and principles in evolutionary genetics. 3. put together all factors into a comprehensive picture of evolution under the joint influence of selection, gene flow, mutation, mating system, and genetic drift. 4. read the current literature in evolutionary biology with understanding. 5. utilize the principles in evolutionary genetics in planning and executing research projects.
Topical Outline
1. Discrete variation. Random mating and Hardy-Weinberg 2. Multi-locus Hardy-Weinberg, linkage disequilibrium 3. Non-random mating 4. Genetic drift 5. Hierarchical population structure 6. Migration 7. Constant selection at single and multiple loci 8. Selection that varies across sexes, space or time 9. Frequency dependent selection. Multi-locus selection 10. Group and kin selection 11. Quantitative traits. Means and deviations. Plasticity 12. Components of variance. Breeding values. Resemblance among relatives 13. Heritability, Response to selection, breeders’ equation. G matrix 14. Measuring selection on phenotypes 15. Fst vs. Qst 16. Mapping quantitative traits
Syllabus
Public CV