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Advanced Organic Chemistry II (Honors)


Course Description

This is the second semester of a two-semester sequence of organic chemistry for honors students covering advanced aspects of nomenclature, structures, and reactions of organic compounds.


Athena Title

ADV ORG CHEM II H


Equivalent Courses

Not open to students with credit in CHEM 2212 or CHEM 2412


Prerequisite

(CHEM 2211 or CHEM 2311H or CHEM 2411) and permission of Honors


Corequisite

CHEM 2312L


Semester Course Offered

Offered spring


Grading System

A - F (Traditional)


Course Objectives

A. Understand the atomic and molecular basis of organic chemistry. B. Understand the impact of organic chemistry on the fields of medicine, pharmacy, dentistry, biology, and physics and its impact on the global economy. C. Understand the fundamental principles of molecular structure and shape as they relate to organic molecules and their properties. D. Understand fundamental acid/base and electrophile/nuleophile reactions in organic chemistry. E. Identify organic molecules by functional group: alkane, alkene, alkyne, haloalkane, alcohol, thiol, ether, sulfide, amine, aldehyde, ketone, carboxylic acid and carboxylic acid derivatives. F. Understand the chemistry of organic functional groups. G. Understand organic nomenclature and symbolism. H. Understand basic principles of valence bond and molecular orbital theory. I. Understand electron delocalization and its effect on stability and reactivity. J. Understand reaction mechanisms and electron movement using the curved-arrow formalism. K. Learn the fundamental principles of functional group interconversion and organic synthesis. L. Understand analytical tools for organic structure determination, including MS, NMR, IR, and UV-Vis.


Topical Outline

I. Mass Spectrometry of Organic Molecules II. Identification of Compounds by Infrared Absorption Spectrometry III. Structural Determination via Nuclear Magnetic resonance Spectrometry IV. Conjugated Dienes a. electronic structure b. UV-Visible Spectrometry c. reactions V. Annulenes and Aromaticity VI. Electrophilic Aromatic Substitution VII. Alcohols and Phenols a. preparation b. reactions c. acid behaviour VIII. Properties and Reactions of Ethers, Epoxides, Thiols and Sulfides IX. Aldehydes and Ketones a. properties b. preparation c. nucleophilic substitution reactions X. Carboxylic Acids and Nitriles a. acid character b. reactions c. hydrolysis of nitriles XI. Carboxylic Acid Derivatives (Amides, Acid Chlorides, Esters, Anhydrides) XII. Carbonyl Alpha Substitution Reactions XIII. Condensation Reactions XIV. Amines


General Education Core

CORE II: Physical Sciences

Syllabus