Course Description
Introductory virology includes viral structure, replication, genetics, and immunity. The mechanism(s) by which viruses enter, spread, and cause diseases in humans and animals. Virus-cell interactions include structural and functional alterations of hosts after virus infection and viral components responsible for these alterations.
Athena Title
VIRA PATH
Equivalent Courses
Not open to students with credit in MMIB 8150
Prerequisite
Permission of department
Semester Course Offered
Offered fall
Grading System
A - F (Traditional)
Course Objectives
This course is designed to give graduate students interested in virology and viral pathogenesis a general and updated review of the current research in virology and an understanding of how viruses cause diseases in humans and animals. This will include, but not be limited to, virus structure, genetics and evolution, immune responses to virus infections, mechanisms of virus invasion, dissemination, replication and the consequences of these processes, i.e. cell injury, cell transformation, or dysfunction.
Topical Outline
Virus structure Virus replication Virus genetics and evolution Immune responses to virus infection Cellular receptors and virus tropism Virulence factors, Virus spreading via blood, lymphatic or nervous routes; Cell injury and dysfunction induced by direct virus replication, induction of apoptosis, or immune mediated responses. Pathogenic mechanism(s) by which viruses cause respiratory, digestive, immunological, neurological, and hematological diseases. Virus induced immunodeficiency and tumorigenesis.