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Fermentation Engineering Laboratory


Course Description

Advanced fermentation principles through the development of mathematical models, design of experiments, and interpretation of results.


Athena Title

FERM ENG LAB


Prerequisite

Permission of department


Semester Course Offered

Offered every year.


Grading System

A - F (Traditional)


Course Objectives

Students will enhance their skills at technical report writing. Students will work in multidisciplinary teams to work on problems in microbial and enzymatic systems. Student will develop skills modeling microbial and enzymatic systems. Students will learn design of fermentation/enzyme experiments and interpretation of results.


Topical Outline

Students will work in multidisciplinary teams on five laboratory modules during the semester. Lectures will directly complement the experiments and lead to an advanced understanding of microbial and enzymatic systems, modeling such systems and interpretation of associated experiments. Students will be expected to 1) investigate the literature, 2) schedule experiment and modify experimental protocol, 3) present their experimental design to instructor(s), 4) conduct experiment, 5) complete written laboratory reports. Students will conduct the following three experiments: 1) batch anaerobic bacterial fermentation 2) genetic transformation of bacteria and batch anaerobic fermentation of transformed microorganism 3) measurement of mass transfer coefficients Students will conduct two of the following experiments: 1) continuous yeast fermentation 2) solid matrix fermentation 3) biodegradation 4) enzyme transformation 5) substrate-limited fed-batch fermentation Additional lecture topics will include: 1) material balances on microbial processes 2) enzyme kinetics 3) microbial growth kinetics 4) mass transport phenomena 5) statistics and cost considerations in medium selection 6) overflow metabolism and fluxes


Syllabus


Public CV