Course Description
Drugs acting on the peripheral nervous system and cardiovascular system, including structure-activity relationships, mechanisms of action, storage, and chemical stability reactions.
Athena Title
Medicinal Chemistry I
Prerequisite
PHRM 3310
Semester Course Offered
Offered spring
Grading System
A - F (Traditional)
Course Objectives
The student should be able to: 1. Identify the drug or drug class given the structure of the drug or a drug prototype 2. List the indications for a drug or drug class 3. Discuss the characteristics of drug-drug, drug-food, drug- lab or drug-disease interactions given a drug or set of drugs 4. Discuss the side effects of a given drug and the mechanism of these side effects 5. Describe the mechanism of action and the pharmacological action of a given drug or drug class 6. Describe the physicochemical (biological stability) and pharmaceutical (chemical stability) properties of a given drug or drug class 7. Describe the structure-activity relationship for a given drug class 8. Describe the ADME characteristics of a given drug or class 9. Describe how physiological and pathophysiological conditions affects the absorption, distribution, metabolism, and elimination (ADME) of a drug 10. Describe how other drugs influence the ADME characteristic of a given drug
Topical Outline
1. Anticonvulsants (AED) 2. General and local anesthetics 3. Benzodiazepines et al 4. Antihistamines (H1, H2 and PPI) 5. Serotonin agents 6. Antidepressants 7. Antipsychotics 8. NSAID’s (non-steroidal anti-inflammatory drugs) and gout 9. Opioids 10. CNS stimulants (ADHD drugs) and hallucinogens 11. Parkinson’s disease drugs 12. Herbal supplements
Syllabus
Public CV