Course Description
A survey of knowledge and analyses of primary literature through lectures, student projects, and presentations to prepare students for graduate-level studies in life sciences. The main focus is on eukaryotic cell biology, with emphasis on cell signaling, cytoskeleton, cell cycle, and cell differentiation.
Athena Title
Adv Genetics Cell Bio Biochem
Semester Course Offered
Offered fall
Grading System
A - F (Traditional)
Course Objectives
Students will achieve: 1) understanding of the current state of knowledge in eukaryotic cell biology 2) training in the genetic, biochemical, molecular, and cellular approaches in application to eukaryotic cell biology 3) exposure to landmark and current literature in cell biology These objectives will be achieved through lectures, discussions, class projects, and reading of primary literature.
Topical Outline
Principles of cell signaling Kinases Plasma membrane-coupled signaling (GPCRs, second messengers, G proteins) C2+ signaling Protease-mediated signaling: Notch TGFbeta, Wnt, Hedgehog signaling Microtubules and motor proteins Mitosis (cytoskeleton perspective) Cilia Microfilaments and myosins Cell Cycle: G1/S transition DNA replication licensing Cell Cycle: G2/M transition and Mitosis Self-renewal and pluripotency Reprogramming and trans-differentiation Biological Microscopy
Syllabus
Public CV