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Topics in Advanced Optical Microscopy


Course Description

A variety of topics in advanced optical microscopy, including the mathematical formalism behind modern three-dimensional microscopy techniques, such as confocal and multiphoton imaging, will be covered. A range of microscopy techniques, including Raman spectroscopy, phase contrast techniques, and Second- Harmonic Generation Microscopy will be examined. Background material in statistical optics and nonlinear optics will be introduced.


Athena Title

Topics in Adv Optical Micros


Prerequisite

PHYS 1212-1212L and MATH 2700


Semester Course Offered

Offered every year.


Grading System

A - F (Traditional)


Course Objectives

1. Calculate the three-dimensional optical transfer functions of confocal and widefield microscopes. 2. Calculate the linear and nonlinear optical response of a model system. 3. Write optical imaging simulations of different microscopy techniques.


Topical Outline

1. The point spread function and optical transfer function 2. Confocal and two-photon microscopy 3. Raman techniques 4. Second-harmonic and third-harmonic generation microscopy 5. Optical coherence and transmission microscopy 6. Superresolution microscopy