Course Description
An overview of synaptic structure/function followed by in-depth discussions and analyses of current and emerging topics in synaptic physiology. Open to graduate students from multiple disciplines with interests in neurotransmission. Although not required, a previous graduate course in physiology or neuroanatomy will be beneficial.
Athena Title
Synaptic Physiology
Semester Course Offered
Offered every odd-numbered year.
Grading System
A - F (Traditional)
Course Objectives
Students will have a detailed understanding of the synapse, including the differences between peripheral synapses such as the neuromuscular junction and central synapses. Students will develop an understanding of the molecular complexities of synaptic modulation, plasticity, and synaptic remodeling. Students will learn about the potential outcomes of pathologies of the synapse. Students will learn and understand the various techniques available to study the synapse.
Topical Outline
Structure and function of the neuromuscular junction Structure and function of a "typical" central synapse Mechanisms of synaptic modulation (presynaptic and postsynaptic) Mechanisms of synaptic plasticity (presynaptic and postsynaptic) Synapse development/remodeling Neurodegeneration Neuroregeneration Synaptic neurotoxins Synaptopathies