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Evolutionary Medicine

Analytical Thinking
Critical Thinking

Course Description

An introduction to the rapidly emerging field of evolutionary medicine. The aim is to better understand the evolutionary nature of human health and disease. The course will apply central concepts from evolutionary biology (such as life history theory, coevolution, genomic conflict, constraints, and trade-offs) to problems in medicine and public health, including antibiotic resistance, aging, cancer, autoimmune disease, and pathogen virulence.


Athena Title

Evolutionary Medicine


Prerequisite

(BIOL 1108 and BIOL 1108L) or (BIOL 2108H and BIOL 2108L)


Semester Course Offered

Offered fall


Grading System

A - F (Traditional)


Student Learning Outcomes

  • Students will learn how to use evolutionary principles to identify why we are vulnerable to common diseases.
  • Students will learn how to evaluate the consequences of pathogen evolution for disease outcomes, treatment, and control.
  • Students will learn how to apply evolutionary principles for novel treatments of cancer and infectious diseases.
  • Students will learn how to evaluate data (graphical and tabular information) in order to formulate hypotheses about mechanisms underlying disease.
  • Students will learn how to apply scientific thinking to assess evidence for different hypothesis regarding specific conditions, such as the menopause or aging.
  • Students will learn how to create testable hypotheses to assess the impacts of evolutionary history in chronic diseases and reproductive health.

Topical Outline

  • Why we get sick?
  • Human evolution and host defense
  • Genetics of susceptibility and personalized medicine
  • Aging
  • Reproduction
  • Cancer and chemotherapy
  • Autoimmunity
  • Microbiomes
  • Circadian rhythms
  • Pathogen virulence
  • Emerging pathogens
  • Vaccines and evolution
  • Drugs and evolution
  • Evolution-proof control

Institutional Competencies

Analytical Thinking

The ability to reason, interpret, analyze, and solve problems from a wide array of authentic contexts.


Critical Thinking

The ability to pursue and comprehensively evaluate information before accepting or establishing a conclusion, decision, or action.



Syllabus