Students will complete three modules addressing the fetal circulation, glucose homeostasis, and the cardiac cycle, and diseases associated with each. Each module will be presented in a clinical context and will use four learning modalities: reading text, viewing animations and illustrations, watching videos, and answering questions.
Athena Title
Fdn of Clinical Medicine II
Non-Traditional Format
This course will be taught 95% or more online.
Prerequisite
BIOL 1104 or BIOL 2104H or BIOL 1108 or BIOL 2108H
Semester Course Offered
Offered fall, spring and summer
Grading System
A - F (Traditional)
Student Learning Outcomes
Students will understand how to explain how and where oxygen molecules move into and out of the blood.
Students will understand how to describe the path of blood flow through the heart in an adult.
Students will understand how to recognize the import role the placenta plays in the transfer of oxygen and carbon dioxide between the mother and fetus.
Students will understand how to describe the role of the ductus arteriosus in the fetus.
Students will understand how to describe the role of the foramen ovale in the fetus.
Students will understand how to describe the role of the ductus venous in the fetus.
Students will understand how to describe the changes that occur in blood flow in the newborn baby and their effects on circulatory function.
Students will understand how to explain the effects of the persistence of either the foramen ovale, ductus arteriosus, or the ductus venosus after birth.
Students will understand how to describe how glucose molecules enter skeletal muscle cells.
Students will understand how to distinguish the prevalence of glucose transporters in skeletal muscle cell membranes in fasted and fed states.
Students will understand how to describe the processes by which glucose transporters and synthesized and are incorporated into the membranes of skeletal muscle cells.
Students will understand how to distinguish the different types of cells in pancreatic islets and the hormones they produce.
Students will understand how to describe the roles of the different glucose transporter proteins in the movement of glucose into skeletal muscle and pancreatic beta cells.
Students will understand how to describe the processes involved in the synthesis and release of insulin.
Students will understand how to differentiate the processes involved in the development of types 1 and 2 diabetes.
Students will understand how to explain the hemoglobin A1C test used in patients with diabetes.
Students will understand how to differentiate insulin-dependent from insulin-independent tissues and explain why the pancreas is insulin independent.
Students will understand how to differentiate diabetes mellitus from diabetes insipidus.
Students will understand how to distinguish diastole from systole and what occurs during each in a normal cardiac cycle.
Students will understand how to describe the pattern of events that result in depolarization and repolarization of cardiac muscle cells during a normal cardiac cycle.
Students will understand how to explain the functions of the sinoatrial and atrioventricular nodes during a normal cardiac cycle.
Students will understand how to explain how changes in pressures within the atria, ventricles, aorta, and pulmonary arteries open and close the atrioventricular and semilunar valves.
Students will understand how to describe the various components of ventricular diastole and systole, and what is occurring during each in a normal cardiac cycle.
Students will understand how to describe the pathophysiology and typical clinical effects of atrial fibrillation.
Topical Outline
Passive diffusion of oxygen and carbon dioxide across alveolar and capillary membranes
How oxygen is transported in the blood and the difference between arterial and venous blood
Path of blood flow through the heart and lungs in the adult
Anatomy and physiology of the placenta
Differences in oxygen content of blood in the umbilical arteries and veins
The location and function of the foramen ovale in the fetus
The location and function of the ductus arteriosus in the fetus
The location and function of the ductus venosus in the fetus
The underlying cause for hypoxic pulmonary vasoconstriction in the fetus
Changes that occur during birth and their effects on the foramen ovale, ductus arteriosus, and ductus venosus
The effects of a patent foramen ovale
The effects of a patent ductus arteriosus and the associated murmur
The clinical effects of a patent ductus venosus
The role of GLUT4 transporters on entry of glucose into skeletal muscle cells
Changes in GLUT4 transporters in skeletal muscle membranes after a meal
Synthesis and incorporation of GLUT4 transporters into cell membranes
Pancreatic alpha and beta cells and their secretions
Role of GLUT2 transporters in the pancreas
Synthesis and release of insulin by the pancreas and its effect on GLUT4 transporters
Synthesis and release of glucagon in response to low glucose concentrations
Pathogenesis of type 1 diabetes and type 2 diabetes
Complications of type 1 diabetes
The basis and use of A1C determinations
The distribution of insulin-dependent and insulin-independent tissues
Diabetes insipidus – its pathogenesis and clinical effects
