Course Description
Designed to train students on three principal objectives, which comprise the second and third stages of a drug discovery pipeline. Beyond its own course objectives, this course is the last of three two-credit course series that encompass aspects of the drug discovery pipeline.
Athena Title
Biopharmaceut Pharmacokinet
Non-Traditional Format
This course will be taught 95% or more online.
Grading System
A - F (Traditional)
Course Objectives
1. What are biopharmaceutics and pharmacokinetics? 2. Will learn how to do non-compartment analysis (NCA) and compartment analysis through various administration routes including oral and intravenous (IV). 3. Will learn how PK relates to the genetics, which is known as pharmacogenetics. 4. Will learn the principles of absorption, distribution, metabolism, and excretion (ADME) and to apply these principles to optimize a patient’s dosage regimen. 5. In terms of drug development, students will identify hypothetical drugs that have suitable PK properties for drug development.
Topical Outline
Module 1. Preclinical Evaluation Module 2. Clinical Evaluation Module 3. Pharmaceutics and Physiology Module 4. Fundamentals of Pharmacokinetics (PK) Module 5. IV Bolus Dose Administration Module 6. IV Infusion Administration Module 7. First Order Absorption Module 8. Drug Distribution Module 9. Renal Excretion and Drug Metabolism Module 10. Hepatic Elimination Module 11. Relationship between PK and Pharmacodynamics (PD) Module 12. Nonlinear Pharmacokinetics Module 13. Drug-Drug Interactions Module 14. Disease/Age/Sex Effects on PK Module 15. Pharmacogenetics
Syllabus