Integrative Cardiovascular and Respiratory Physiology
VPHY 4500/6500
3 hours
Integrative Cardiovascular and Respiratory Physiology
Course Description
An examination of the cardiovascular and respiratory systems using cellular physiology and organ-organ interactions. Physiological and pathological adaptations of the cardiovascular and respiratory systems will be explored in the context of physical activity, disease, and aging. Regenerative medicine and rehabilitation physiology discussions will investigate evidence-based treatments and emerging technologies to diagnose and prevent disease.
Additional Requirements for Graduate Students: Graduate students will be required to complete an end-of-term research report on a cardiovascular-respiratory topic of their choice. Graduate students are expected to complete a literature review and appropriately cite their research report.
Athena Title
Integr Cardiovasc Resp Physiol
Prerequisite
VPHY 3100 or VPHY 3100E or VPHY 3107-3107D or CBIO 2210-2210L or CBIO 3710 or EHSC 2100 or PMCY 3000 or PMCY 3000E or POUL 4175 or POUL 4200/6200-4200L/6200L or WILD 4400/6400 or permission of department
Semester Course Offered
Offered fall
Grading System
A - F (Traditional)
Student learning Outcomes
Students will demonstrate comprehension of cardiovascular physiology, the regulation of cardiac output and blood flow throughout the body.
Students will demonstrate comprehension of respiratory physiology, the gas exchange in the lungs and peripheral tissue.
Students will demonstrate comprehension of cardiovascular and respiratory system integration in the context of physical activity and disease.
Students will become proficient in searching traditional literature resources to evaluate data (e.g., pubmed/science library).
Students will critically evaluate scientific literature on cardiovascular and respiratory physiology.
Students will demonstrate how to generate a research question, form a hypothesis, and design a study to address the hypothesis using knowledge bases built throughout the course relating to cardiovascular and respiratory physiology.
Students will demonstrate an ability to problem-solve cardiovascular and respiratory physiology challenges in a team setting.
Students will perform end-of-year formal presentation to discuss research question/hypothesis/study design.
Topical Outline
i) Cellular physiology of cardiac muscle contraction and blood pressure
ii) Control of cardiac function during physical activity
iii) Cellular physiology of blood flow control
iv) Control of circulation during physical activity
v) Vascular adaptations to disease, aging, and physical activity
vi) Respiratory mechanics
vii) Gas exchange and transport
viii) Cardiovascular and respiratory system interactions
ix) Metabolism of the cardiovascular and respiratory muscles
x) Heart failure
xi) Diabetes
xii) Hypertension
xiii) Regenerative medicine for cardiovascular disease
