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Cell Biology


Course Description

Structure and function of cells: cell architecture and organization, cell cycle, membrane phenomena, organellogenesis, energy transduction, and cellular control mechanisms.


Athena Title

Cell Biology


Equivalent Courses

Not open to students with credit in CBIO 3400H


Prerequisite

BCMB 3100 or BCMB 3100E or BCMB 3100H or BCMB 4010/6010


Pre or Corequisite

GENE 3200-3200D or GENE 3200H or GENE 3200E


Semester Course Offered

Offered fall, spring and summer


Grading System

A - F (Traditional)


Course Objectives

1) Be able to explain important cellular structures, processes, and mechanisms. 2) Be able to interpret cell biology data, design experiments to answer cell biology questions, and predict outcomes of these experiments. 3) Be able to communicate knowledge about cell biology to other science students and the general public.


Topical Outline

1) Membranes transport a) Biological membranes b) Permeability and transport c) Channels and membrane potential 2) Cell signaling a) G-protein coupled receptor signaling b) Receptor tyrosine kinase signaling c) Phosphoinositide signaling 3) Gene expression in cells a) Nuclear structure and organization b) Nucleocytoplasmic transport c) Chromatin and nuclear genome structure d) Transcription e) mRNA processing f) Translation g) Mitochondrial genome structure h) Mitochondrial protein import 4) Secretory pathway and vesicular traffic a) Endoplasmic reticulum: protein import and glycosylation b) Endoplasmic reticulum: protein folding and quality control c) Traffic: ER to Golgi and Golgi to ER d) Endocytosis e) Exocytosis 5) Cytoskeleton a) Actin and microfilaments b) Myosin motors c) Tubulin and microtubules d) Microtubular motors 6) Cell Cycle a) Cell Cycle: S phase b) Cell Cycle: M phase and cytokinesis c) Cell Cycle: checkpoints d) Cancer cells 7) Advanced topics a) Stem cells b) Apoptosis


Syllabus