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Microbial Genetics and Genomics


Course Description

Bacterial genome composition and analysis with emphasis on annotation, metabolic function, and homology. Online programs in the computer lab target DNA sequences, protein sequences, and metabolic pathways. Bioinformatic exploration will enhance comprehension of important concepts and provide a foundation for basic and advanced courses in microbiology, biochemistry, and genetics.

Additional Requirements for Graduate Students:
Graduate students must write a term paper pertaining to topic(s) covered in class.


Athena Title

Microbial Genetics and Genomic


Prerequisite

BIOL 1107 or BIOL 1107E or BIOL 2107H or BIOL 1108 or BIOL 2108H or permission of department


Semester Course Offered

Offered fall


Grading System

A - F (Traditional)


Student Learning Outcomes

  • Students will know how to use online scientific computer programs and resources to enhance understanding of fundamental aspects of genetics, microbiology, and biochemistry.
  • Students will improve skills related to finding, reading, and understanding current scientific literature and web-based information related to microbial genetics and genomics.
  • Students will improve writing and presentation skills. The emphasis will be on clear, succinct, and precise communication.
  • Students will know how to use in-depth examples and hands-on bioinformatic exploration to enhance comprehension of important concepts.

Topical Outline

  • Genes and proteins
  • Central Dogma
  • Coding Sequences
  • Open Reading Frames
  • Annotation
  • Ribosome Binding Sites
  • Amino acids
  • Protein structures
  • Codon Usage
  • Sequence Analysis
  • Homology searches
  • Genome architecture
  • Regulatory sequences
  • Gene neighborhoods
  • Synteny
  • Current Literature and Examples
  • Regulatory topics
  • Metabolic Topics
  • Transcriptional Regulators
  • Protein - DNA interactions
  • Team Projects
  • Class Presentations

Syllabus