Course Description
Vertebrate endocrinology and the principles of chemical integration, emphasizing the physiology of regulatory mechanisms and the cellular and molecular bases of hormone action.
Additional Requirements for Graduate Students:
Lecture examinations require more background reading. A written report on some pre-approved aspect of endocrinology is required.
Athena Title
ENDOCRINOLOGY
Prerequisite
[(BIOL 1103 and BIOL 1103L) or BIOL 1107-1107L or BIOL 2107H-2107L] and [(BIOL 1104 and BIOL 1104L) or BIOL 1108-1108L or BIOL 2108H-2108L]
Undergraduate Pre or Corequisite
BCMB(BIOL)(CHEM) 3100
Semester Course Offered
Not offered on a regular basis.
Grading System
A - F (Traditional)
Course Objectives
At the end of the semester, students will: 1. Know the gross and histological anatomy of selected endocrine glands and tissues. 2. Learn the basic function of many endocrine systems. 3. Be able to analyze current data and clinical literature. 4. Be able work in collaboration with others to solidify endocrine concepts presented as case studies. 5. Demonstrate writing skills appropriate for an split-level course.
Topical Outline
Introduction; What is endocrinology? Classification of hormones Hormone synthesis, transport & feedback regulation How does a hormone exert its effects? Membrane receptors: G proteins Catalytic (kinase linked) receptors; Intracellular receptors Multiple organ effects Mechanisms of disease Endocrine Pancreas: Insulin Energy metabolism & diabetes mellitus GI hormones Receptor kinetics Calcitonin & Vitamin D Regulation of Ca2+ and PO4 Vasopressin (Antidiuretic Hormone) AVP & water balance Aldosterone & AVP: Sodium & water balance Hormonal control of blood pressure Sexual differentiation Human Reproduction Endocrine Overview Receptors Immunoassays Endocrine Biosynthesis Pancreas Gastrointestinal Endocrinology Adrenal Medulla Adrenal Cortex Thyroid Calcium and Bone Physiology Parathyroid Sodium and Water Regulation Neurohypophysis Renin-Angiotensin System Sex Differentiation and Puberty Male Reproduction Female Reproduction Pregnancy and Lactation Infertility The course syllabus is a general plan for the course; deviations announced to the class by the instructor may be necessary.