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Pathophysiology I


Course Description

Fundamental mechanisms of human disease process, including manifestation, diagnosis, and treatment. Emphasis on central nervous system, musculoskeletal, oncological, neurological, dermatological, and gastrointestinal diseases.


Athena Title

PATHOPHYSIOLOGY


Prerequisite

Permission of department


Corequisite

PHRM 3050 and PHRM 3400


Semester Course Offered

Offered every year.


Grading System

A - F (Traditional)


Course Objectives

Pathophysiology is a team taught course. Each instructor is responsible for preparing exam questions on their lecture material. The course coordinator will administer exams and assign course grades. When the student has completed this course in human pathophysiology, he/she should be able to: 1. Define the common medical terms used to describe pathological conditions. 2. Define each of the five components of the disease process: epidemiology, etiology, pathophysiology, clinical manifestations, and outcome. 3. For specific disease syndromes: describe the mechanism of the disease; list the major clinical manifestations of diseases; describe the current treatment; and describe methods of prevention of the disease. 4. Describe the various types of diagnostic tests and procedures that help a practitioner in making a diagnosis of the disease and decide on a patient's treatment. 5. Discuss the role of drug therapy in the treatment of each disease state discussed. Testing and grading: Three one hour (100 point, multiple choice/short answer) exams and one final exam(100 points) will be administered during the semester. A total of 400 points may be earned in the course (400-360 points=A, 359-320 points=B, 319-280 points=C, 279-240 points=D,less than 240 points=F. To make up an exam, students must have an excused absence signed by the Assoc. Dean, and must take the make-up exam within 5 days of returning to class. Questions will not be answered during the exam. Students may not wear bill caps during an exam. Questions concerning the grading of an exam must be asked within 5 days of the grades for that exam being posted. Class attendance is required. Absences require a valid excuse signed by the Associate Dean. The student is responsible for the material he/she misses during an absence.


Topical Outline

The following topics will be covered: I. Adaptation of the cell to changing conditions A. Atrophy, hypertrophy, hyperplasia, dysplasia, metaplasia, neoplasia B. Inflammation, necrosis, apoptosis and cell death C. Neoplasia, carcinogenesis and the biology of cancer II. Breast cancer, gynecological cancers, colon cancer, prostate cancer, testicular cancer, and lung cancer III. Dermatological diseases IV. Muscle Disorders A. Myasthenia gravis B. Muscular dystrophy C. Multiple sclerosis D. Amyotrophic lateral sclerosis V. Nervous System Disorders A. Nerve injury and repair B. Cranial and peripheral nerve disorders C. Traumatic damage to the spinal cord D. Central Nervous system trauma E. Neurological diseases F. Psychiatric disorders/diseases VI. Sensory Disorders A. Diseases of the eye B. Diseases of the ear and vestibular apparatus VII. Gastrointestinal Disorders: A. Reflux/Peptic ulcer disease B. Stress induced damage C. Inflammatory bowel disease D. Diarrhea/constipation E. Nausea/vomiting VIII. Pancreatitis