Course ID: | PHRM 4211/6211. 4 hours. |
Course Title: | Pharmaceutics II: Biopharmaceutics and Pharmacokinetics |
Course Description: | Basic concepts associated with drug absorption, distribution,
metabolism, excretion, and transport with an emphasis on
compartmental modeling related to dosing of drugs. Specific
disease states that alter drug disposition. |
Oasis Title: | Biopharm and Pharmacokinetics |
Prerequisite: | PHRM 4200/6200 and PHRM 3300 |
Corequisite: | PHRM 4040 |
Semester Course Offered: | Offered spring semester every year. |
Grading System: | A-F (Traditional) |
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Course Objectives: | 1. Understand basic concepts associated with drug absorption,
distribution, metabolism, excretion and transport.
2. Calculate and interpret pharmacokinetic parameters.
3. Predict drug interactions and be able to explain the
mechanism(s) involved.
4. Determine when to obtain blood levels and how to interpret
the blood levels
5. Determine the effects of renal, hepatic and cardiovascular
disease on pharmacokinetics of drugs
6. Examine pharmacokinetics in special populations
7. Examine the influene of pharmacogenomics on
pharmacokinetics/pharmacodynamics |
Topical Outline: | Principles of drug absorption, distribution, metabolism,
excretion, and transport
Compartmental modeling
Drug interactions
Pharmacodynamics
Pharmacokinetic basis for dosing of drugs
Influence of disease states on pharmacokinetics
Dosing adjustments in disease states and hemodialysis
Pharmacokinetics in geriatric and pediatric patients
Pharmacogenomics and clinical implications |
Honor Code Reference: | All academic work must meet the standards contained in “A
Culture of Honesty.” Students are responsible for informing
themselves about those standards before performing any academic
work. Any student found in violation of the University’s
academic honesty policies will be referred to the Student
Academic Affairs Committee. |