This course is intended for graduate students at any level and 
from any field of study with an interest in genome 
technologies. 
Course will emphasize experimental design and use of current 
techniques.
Course will use examples from current literature.
Upon successful completion of this course, the student should 
be able to:
• Describe design experiments using the technologies covered.
• Compare, contrast and evaluate different instrumentation and 
approaches used to obtain the desired experimental data.
• Locate and critically evaluate studies using genome 
technologies from the current literature.

Core technologies and methods that are covered include:
•	Massively Parallel DNA Sequencing 
o	Illumina (Solexa) Genome Analyzer
o	Ion Torrent Proton and PGM
o	Legacy data/techniques
	Roche (454) Genome Sequencer
	Applied Biosystems SOLID
o	New Technologies 
	Oxford Nanopore
	Genia and Other Nanopore Platforms
o	De Novo Sequencing
o	Target Enrichment and Sequence Capture
o	RADseq
o	Amplicon Sequencing
o	Metagenomics
o	Gene Expression and Transcriptomes
•	Analyzing Massively Parallel DNA Sequence Data
o	Demultiplexing
o	Data Quality Trimming
o	16S Microbial Community Analysis
o	De Novo Assemblies
o	SNP Calling
o	Software 
	Geneious
	Galaxy

Examples of additional technologies that could be covered, 
based on the interests of specific groups of students, 
include:

•	Microarrays and Quantitative PCR 
o	Affymetrix
o	Agilent
o	NimbleGen
o	Gene Expression
o	Sequence Capture
o	Tiling Arrays
•	Microsatellite DNA Loci 
o	Enrichment
o	Random Genome Sequencing for Marker Discovery
o	Primer Design
o	Genotyping by Capillary Electrophoresis
o	Analyzing the Data with GeneMapper
•	SNP Genotyping
o	Genotype by Sequencing
o	High Resolution Melt & other legacy methods

Students are expected to follow the UGA Student Honor Code in 
all works as detailed in A Culture of Honesty: “I will be 
academically honest in all of my academic work and will not 
tolerate academic dishonesty of others.”  A Culture of Honesty, 
the University's policy and procedures for handling cases of 
suspected dishonesty, can be found at 
http://www.uga.edu/honesty/.